Real-world outcomes of anti-EGFR therapy in advanced non-small cell lung cancer EGFR mutated in Peru.
Marco Gálvez-NinoRossana RuizKátia Roque PerezOfelia CoanquiNatalia ValdiviesoMivael OliveraApar Kishor GantiLuis MasPublished in: Thoracic cancer (2022)
Our study demonstrates that erlotinib for advanced NSCLC harboring EGFR-activating mutations is effective even in patients usually excluded from clinical trial, like those previously exposed to one or more lines of chemotherapy or with brain metastases.
Keyphrases
- advanced non small cell lung cancer
- epidermal growth factor receptor
- small cell lung cancer
- brain metastases
- tyrosine kinase
- clinical trial
- end stage renal disease
- newly diagnosed
- chronic kidney disease
- peritoneal dialysis
- signaling pathway
- squamous cell carcinoma
- type diabetes
- patient reported outcomes
- adipose tissue
- weight loss
- insulin resistance