Comparatively analyzing the liver-specific transcriptomic profiles in Kunming mice afflicted with streptozotocin- and natural food-induced type 2 diabetes mellitus.
Yanjun WuXiang-Xing ZhuArome Solomon OdibaZisheng LinJiancong WenDaoyuan GongJing LiangShuguang WuGanqiu LanPublished in: Molecular biology reports (2021)
A high fat and high carbohydrate diet combined with a low dose of STZ can effectively induce diabetes in Kunming mice despite the abnormal expressions of genes in the liver. The differentially expressed genes were related to metabolism mediated by p53.
Keyphrases