Bearing variant alleles at uridine glucuronosyltransferase polymorphisms UGT2B7 -161C > T (rs7668258) or UGT1A4*3 c.142 T > G (rs2011425) has no relevant consequences for lamotrigine troughs in adults with epilepsy.
Nada BožinaIvana Šušak SporišIva Klarica DomjanovićLana GanociLivija ŠimičevićMila LovrićZrinka Čolak RomićŽeljka Petelin GadžeVladimir TrkuljaPublished in: European journal of clinical pharmacology (2023)
Dose-adjusted lamotrigine troughs in epilepsy patients with variant UGT2B7 -161C > T or UGT1A4*3 c.142 T > G alleles are equivalent to those in their respective wt peers.
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