The role of the glycosyl moiety of myricetin derivatives in anti-HIV-1 activity in vitro.
Joseph T OrtegaAlirica I SuárezMaria L SerranoJani BaptistaFlor H PujolHéctor Rafael RangelPublished in: AIDS research and therapy (2017)
The results suggest that glycosylated moiety might enhance the anti-HIV-1 activity of myricetin, probably by favoring the internalization of the flavonoid into the cell. The inhibition of the HIV-1 reverse transcriptase is likely responsible for the antiviral activity.