Garmultin-A Incites Apoptosis in CB3 Cells Through miR-17-5p by Attenuating Poly (ADP-Ribose) Polymerase-1.

Jianfei QiuLi ChenJue YangKrishnapriya M VarierBabu GajendranYao YaoWuling LiuJingrui SongQing RaoQun LongChunmao YuanXiaojiang HaoYanmei Li

Published in: Dose-response : a publication of International Hormesis Society (2022)

These results provide critical insights that GA could induce apoptosis in CB3 cells through targeting miR-17-5p by attenuating PARP-1. Thus, GA could act as a novel therapeutic agent for erythroleukemia.

Keyphrases

cell cycle arrest
induced apoptosis
cell death
endoplasmic reticulum stress
pet ct
pi k akt
oxidative stress
dna damage
dna repair
cell proliferation
drug delivery
cancer therapy
structural basis