Preparation of loratadine nanocrystal tablets to improve the solubility and dissolution for enhanced oral bioavailability.

Jing LiYingping ZhouMayinuer AishaJingyan WuHongyun WangFang HuangMin-Jie Sun

Published in: The Journal of pharmacy and pharmacology (2021)

The nanocrystal tablets could significantly improve the oral bioavailability of loratadine, which would also be a promising approach to enhance the solubility of insoluble drugs.

Keyphrases

water soluble
molecularly imprinted
mass spectrometry
high resolution