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CSF levels of SNAP-25 are increased early in Creutzfeldt-Jakob and Alzheimer's disease.

Steffen HalbgebauerPetra SteinackerSophie HenggePatrick OecklMarkus OttoSarah Anderl-StraubJolina LombardiChristine A F Von ArnimArmin GieseAlbert C LudolphMarkus Otto
Published in: Journal of neurology, neurosurgery, and psychiatry (2022)
Using the novel established CSF SNAP-25 ELISA, we here demonstrate the applicability of SNAP-25 as an early synaptic biomarker for both AD and CJD with a possible prognostic value in patients with CJD.
Keyphrases
  • cognitive decline
  • prefrontal cortex