FSTL3 partially mediates the association of increased nonalcoholic fatty liver disease fibrosis risk with acute myocardial infarction in patients with type 2 diabetes mellitus.
Wenfei DuanRuixiao ShiFang YangZhoujunhao ZhouLihong WangZhe HuangShufei ZangPublished in: Cardiovascular diabetology (2023)
NAFLD fibrosis was closely associated with AMI in T2DM patients. FSTL3 expression was enriched in the liver of NAFLD patients with significant and advanced fibrosis, and serum FSTL3 partially mediated the association of increased liver fibrosis risk with AMI in T2DM patients.
Keyphrases
- acute myocardial infarction
- liver fibrosis
- end stage renal disease
- newly diagnosed
- ejection fraction
- chronic kidney disease
- peritoneal dialysis
- prognostic factors
- heart failure
- left ventricular
- percutaneous coronary intervention
- coronary artery disease
- metabolic syndrome
- adipose tissue
- acute coronary syndrome
- insulin resistance
- binding protein