AIM2 deletion enhances blood-brain barrier integrity in experimental ischemic stroke.
Si-Yi XuHui-Jie BianShu ShuSheng-Nan XiaYue GuMei-Juan ZhangYun XuXiang Cao
Published in: CNS neuroscience & therapeutics (2021)
Our findings indicated that inhibiting AIM2 preserved the BBB integrity after ischemic stroke, at least partially by modulating STAT3 activation and that AIM2 may be a promising therapeutic target for cerebral ischemic stroke.