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Validation and Refinement of Chronic Lung Allograft Dysfunction Phenotypes in Bilateral and Single Lung Recipients.

Ariss DerHovanessianJamie L ToddAlice ZhangNing LiAradhna MayalallC Ashley Finlen CopelandMichael ShinoElizabeth N PavliskoW Dean WallaceAric GregsonDavid J RossRajan SaggarJoseph P LynchJohn BelperioLaurie D SnyderScott M PalmerS Samuel Weigt
Published in: Annals of the American Thoracic Society (2017)
We independently validated the prognostic significance of FVC loss for bilateral lung recipients and demonstrated that this approach to CLAD classification also confers prognostic information for single lung transplant recipients. Improved understanding of these discrete phenotypes is critical to the development of effective therapies.
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