Incidence of alopecia in brain tumour patients treated with pencil scanning proton therapy and validation of existing NTCP models.
Simona GaitoLaura CellaAnna FranceSerena MontiGillian WhitfieldPeter SitchNeil BurnetEd SmithGiuseppe PalmaMarianne AznarPublished in: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology (2024)
Despite the reasonable sensitivity and specificity of the NTCP models for RIA in the validation cohort, our study emphasizes the significance of differences between the cohorts utilized for model development and validation. Specifically, variations in the reporting of clinical outcomes inevitably jeopardize the validation of NTCP models. A standardize and objective RIA scoring system is essential.