Transgender Girls Grow Tall: Adult Height Is Unaffected by GnRH Analogue and Estradiol Treatment.
Lidewij Sophia BoogersChantal Maria WiepjesDaniel Tatting KlinkIlse HellingaAdrianus Sarinus Paulus van TrotsenburgMartin den HeijerSabine Elisabeth HannemaPublished in: The Journal of clinical endocrinology and metabolism (2022)
Growth decelerated during GnRHa and accelerated during GAHT. After regular-dose treatment, adult height was slightly lower than predicted at start of GnRHa, likely due to systematic overestimation of PAH as described in boys from the general population, but not significantly different from target height. High-dose EE resulted in greater reduction of adult height than high-dose estradiol, but this needs to be weighed against possible adverse effects.