Metal-Free C-H Functionalization of Alkanes by Aryldiazoacetates.
Cecilia TortoretoDaniel RacklHuw M L DaviesPublished in: Organic letters (2017)
Thermally induced reactions of donor/acceptor diazo compounds generate carbene intermediates capable of C-H functionalization reactions of alkanes. A variety of C-H insertion products were obtained in moderate to good yields and in certain cases with good site selectivity, favoring the functionalization of the more highly substituted C-H bond.