The Influence of Pubertal Development on Autoantibody Appearance and Progression to Type 1 Diabetes in the TEDDY Study.

Katharina WarnckeRoy TamuraDesmond A SchatzRiitta VeijolaAndrea K SteckBeena AkolkarWilliam HagopianJeffrey P KrischerÅke LernmarkMarian J RewersJorma ToppariRichard McIndoeAnette-G ZieglerKendra VehikMichael J HallerHelena Elding Larsson

Published in: Journal of the Endocrine Society (2024)

Rapid weight gain during puberty is associated with development of islet autoimmunity. Puberty itself had no significant influence on the appearance of autoantibodies or type 1 diabetes. Further studies are needed to better understand the underlying mechanisms.

Keyphrases

type diabetes
weight gain
glycemic control
birth weight
cardiovascular disease
systemic lupus erythematosus
skeletal muscle
case control
quantum dots