Compositional structural brain signatures capture Alzheimer's genetic risk on brain structure along the disease continuum .

Patricia GeniusM Luz CalleBlanca Rodríguez-FernándezCarolina MinguillonRaffaele CacciagliaDiego Garrido-MartinManel EstellerArcadi NavarroJuan Domingo GispertJuan-Domingo Gispertnull nullnull null

Published in: medRxiv : the preprint server for health sciences (2024)

The findings underscore the complex interplay between genetics and disease stages in shaping brain structure, which could inform targeted preventive strategies and interventions in preclinical AD.

Keyphrases

resting state
white matter
functional connectivity
genome wide
multiple sclerosis
gene expression
cognitive decline
drug delivery
cancer therapy
mesenchymal stem cells
blood brain barrier