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Compositional structural brain signatures capture Alzheimer's genetic risk on brain structure along the disease continuum .

Patricia GeniusM Luz CalleBlanca Rodríguez-FernándezCarolina MinguillonRaffaele CacciagliaDiego Garrido-MartinManel EstellerArcadi NavarroJuan Domingo GispertJuan-Domingo Gispertnull nullnull null
Published in: medRxiv : the preprint server for health sciences (2024)
The findings underscore the complex interplay between genetics and disease stages in shaping brain structure, which could inform targeted preventive strategies and interventions in preclinical AD.
Keyphrases
  • resting state
  • white matter
  • functional connectivity
  • genome wide
  • multiple sclerosis
  • gene expression
  • cognitive decline
  • drug delivery
  • cancer therapy
  • mesenchymal stem cells
  • blood brain barrier