Trauma diagnostic-related target proteins and their detection techniques.
YiLiu WeiXiaohan RenZhitao YuanJie HongTao WangWeizhi ChenYuqing XuJinwang DingJun LinWenqian JiangPeng ZhangQiaoyi WuPublished in: Expert reviews in molecular medicine (2024)
Trauma is a significant health issue that not only leads to immediate death in many cases but also causes severe complications, such as sepsis, thrombosis, haemorrhage, acute respiratory distress syndrome and traumatic brain injury, among trauma patients. Target protein identification technology is a vital technique in the field of biomedical research, enabling the study of biomolecular interactions, drug discovery and disease treatment. It plays a crucial role in identifying key protein targets associated with specific diseases or biological processes, facilitating further research, drug design and the development of treatment strategies. The application of target protein technology in biomarker detection enables the timely identification of newly emerging infections and complications in trauma patients, facilitating expeditious medical interventions and leading to reduced post-trauma mortality rates and improved patient prognoses. This review provides an overview of the current applications of target protein identification technology in trauma-related complications and provides a brief overview of the current target protein identification technology, with the aim of reducing post-trauma mortality, improving diagnostic efficiency and prognostic outcomes for patients.
Keyphrases
- trauma patients
- acute respiratory distress syndrome
- traumatic brain injury
- healthcare
- risk factors
- protein protein
- drug discovery
- public health
- binding protein
- extracorporeal membrane oxygenation
- acute kidney injury
- small molecule
- cardiovascular events
- end stage renal disease
- type diabetes
- physical activity
- newly diagnosed
- emergency department
- intensive care unit
- case report
- mechanical ventilation
- mental health
- coronary artery disease
- pulmonary embolism
- ejection fraction
- cardiovascular disease
- loop mediated isothermal amplification
- septic shock
- smoking cessation
- combination therapy