Enzymatically promoted release of organic molecules linked to magnetic nanoparticles.
Chiara LambruschiniSilvia VillaLuca BanfiFabio CanepaFabio MoranaAnnalisa ReliniPaola RianiRenata RivaFulvio SilvettiPublished in: Beilstein journal of nanotechnology (2018)
Magnetite-based magnetic nanoparticles have been successfully coupled to an organic system constituted of a fluorescent molecule, a tripeptide specifier and a spacer. The system is able to selectively release the fluorescent molecule upon targeted enzymatic hydrolysis promoted by a lysine/arginine specific protease.