Obesity aggravates the role of C-reactive protein on knee pain: A cross-sectional analysis with NHANES data.
Ling LuoMingzi LiWenlong HuangSiying ZhangJianbo SunBingsong ZhangWei HuHaibing YuPublished in: Immunity, inflammation and disease (2024)
Obesity mediated the systemic inflammation results in knee pain in US adults. Moreover, higher BMI was associated with higher knee pain risk in different degree CRP subgroups, supporting an important role of weight loss in reducing knee pain caused by systemic inflammation.
Keyphrases
- chronic pain
- weight loss
- total knee arthroplasty
- pain management
- neuropathic pain
- knee osteoarthritis
- metabolic syndrome
- insulin resistance
- type diabetes
- weight gain
- anterior cruciate ligament
- anterior cruciate ligament reconstruction
- body mass index
- high fat diet induced
- spinal cord injury
- adipose tissue
- electronic health record
- deep learning
- machine learning
- postoperative pain
- glycemic control