Can CSF spectrophotometry for "Xanthochromia" be used to detect leaking subarachnoid aneurysms in patients with sickle cell anemia with negative MRI or CT angiogram despite hyperbilirubinemia?

Wan Yung SiuWilliam ThomasRikin TrivediAlexandra HoganUmbareen SiddiqiAnita SarkerMartin Wolfgang Besser

Published in: Clinical case reports (2020)

CSF (Cerebrospinal Fluid) xanthochromia by spectroscopy should not be dismissed in the context of hyperbilirubinemia in a patient with sickle cell anemia. Xanthochromia detected by spectrophotometry offers a vital clue that further invasive diagnosis is required.

Keyphrases

cerebrospinal fluid
contrast enhanced
iron deficiency
chronic kidney disease
magnetic resonance imaging
computed tomography
case report
high resolution
image quality
single molecule
dual energy
magnetic resonance
positron emission tomography
diffusion weighted imaging
mass spectrometry