Design of a Stem Cell-Based Therapy for Ependymal Repair in Hydrocephalus Associated With Germinal Matrix Hemorrhages.

Luis M Rodriguez-Perez Betsaida Ojeda-Pérez Javier López-de-San-SebastiánMaría García-BonillaMarcos González-GarcíaBeatriz Fernández-Muñoz Rosario Sanchez-Pernaute María Luisa García-Martín Dolores Domínguez-Pinos Casimiro Cárdenas Antonio Jesús Jiménez Patricia Paez-Gonzalez

Published in: Stroke (2024)

In GMH/PHH, the ependyma can be restored and edema decreased from either neural stem cell or EpP transplantation in vitro and in vivo. Mesenchymal stem cell pretreatment improved the success of the ependymal restoration.

Keyphrases

stem cells
cell therapy
mesenchymal stem cells
bone marrow
subarachnoid hemorrhage
cerebrospinal fluid
brain injury