Magnesiation of Aryl Fluorides Catalyzed by a Rhodium-Aluminum Complex.
Ikuya FujiiKazuhiko SembaQiao-Zhi LiShigeyoshi SakakiYoshiaki NakaoPublished in: Journal of the American Chemical Society (2020)
We report the magnesiation of aryl fluorides catalyzed by an Al-Rh heterobimetallic complex. We show that the complex is highly reactive to cleave the C-F bonds across the polarized Al-Rh bond under mild conditions. The reaction allows the use of an easy-to-handle magnesium powder to generate a range of arylmagnesium reagents from aryl fluorides, which are conventionally inert to such metalation compared with other aryl halides.
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