Chlamydia pneumoniae Infection Exacerbates Atherosclerosis in ApoB100only/LDLR-/- Mouse Strain.

Ildikó Lantos Valéria Endrész Dezső Péter Virok Andrea Szabó Xinjie Lu Gabriella Spengler Katalin Burian

Published in: BioMed research international (2018)

Similar to ApoE-/- mice, ApoB100only/LDLR-/- mice with more human-relevant serum lipoprotein composition develop increased atherosclerosis after Cpn infections; thus this mouse strain can be used as a model of infection-related atherosclerosis enhancement and can provide further evidence for the proatherogenic influence of Cpn in mice.

Keyphrases

high fat diet induced
cardiovascular disease
endothelial cells
wild type
insulin resistance
metabolic syndrome
low density lipoprotein