Electrophilic and Nucleophilic Aromatic Substitutions are Mechanistically Similar with Opposite Polarity.
Mieczyslaw MakoszaPublished in: Chemistry (Weinheim an der Bergstrasse, Germany) (2020)
Confrontation of the recently formulated general mechanism of nucleophilic substitution in electron-deficient arenes with the well-known mechanism of electrophilic substitution revealed that these fundamental processes are mechanistically identical but proceed according to opposite polarity-an Umpolung relation. In this viewpoint this apparently controversial concept is supported by discussion of a variety of experimental results.
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