Time of Liver Function Abnormal Identification on Prediction of the Risk of Anti-tuberculosis-induced Liver Injury.
Deliang HuangJinghan PengLin LeiYuanyuan ChenZhibing ZhuQingxian CaiYongcong DengJun ChenPublished in: Journal of clinical and translational hepatology (2022)
The time to identification of LFT was positively correlated with DILI, liver failure, and anti-TB drug resistance. The risk of DILI and liver failure was significantly increased in the late identification group with abnormal LFT identified after 8 weeks compared with 4 and 8 weeks. Early monitoring of LFT is recommended for patients without the high-risk factor of DILI after anti-TB treatment is initiated.
Keyphrases
- liver failure
- hepatitis b virus
- mycobacterium tuberculosis
- drug induced
- end stage renal disease
- bioinformatics analysis
- newly diagnosed
- risk factors
- chronic kidney disease
- prognostic factors
- patient reported outcomes
- hepatitis c virus
- hiv aids
- human immunodeficiency virus
- hiv infected
- preterm birth
- smoking cessation