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Long term term follow-up of tyrosine kinase inhibitors treatments in inoperable or relapsing diffuse type tenosynovial giant cell tumors (dTGCT).

Mehdi BrahmiPhilippe Alexandre CassierArmelle DufresneSylvie ChabaudMarie KaranianAlexandra MeurgeyAmine BouhamamaFrancois GouinGualter VazJerome GarretMarie-Pierre SunyachAurélien DupréPerrine Marec-BerardNadège CorradiniDavid PerolIsabelle Ray-CoquardJean Yves Blay
Published in: PloS one (2020)
CSF1R TKI or Ab provide prolonged tumor control and symptom relief for a majority of patients with inoperable or relapsing dTGCT, in first and subsequent lines. Multiple lines are required for close to 50% of patients with relapsing dTGCT.
Keyphrases
  • giant cell
  • multiple sclerosis
  • disease activity
  • locally advanced
  • chronic myeloid leukemia
  • preterm infants
  • tyrosine kinase
  • low grade
  • rheumatoid arthritis
  • radiation therapy
  • gestational age
  • high grade