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Aspirin hypersensitivity diagnostic index (AHDI): In vitro test for diagnosing of N-ERD based on urinary 15-oxo-ETE and LTE 4 excretion.

Lucyna MastalerzGabriela TrądPiotr SzatkowskiAdam ĆmielAnna GieliczRadosław KacorzykHanna PluteckaJoanna SzaleniecAgnieszka Gawlewicz-MroczkaBogdan JakiełaMarek Sanak
Published in: Allergy (2024)
We confirmed 15-oxo-ETE as a second to cysteinyl leukotrienes biomarker of N-ERD. An index based on these eicosanoids corrected for sex and Lund-Mackay score has a similar diagnostic value as gold standard oral aspirin challenge in the studied group of patients with asthma.
Keyphrases
  • low dose
  • cardiovascular events
  • antiplatelet therapy
  • chronic obstructive pulmonary disease
  • lung function
  • drug induced
  • coronary artery disease
  • silver nanoparticles
  • allergic rhinitis
  • atrial fibrillation