Cancer stage and pack-years, but not p16 or HPV, are relevant for survival in hypopharyngeal and laryngeal squamous cell carcinomas.
Valerie DahmAndrea HaitelAlexandra KaiderIsabella StaniszAndrea BeerClaudia LillPublished in: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery (2018)
The data suggest that tumor stage and nicotine exposure seem to have the highest impact on survival in hypopharyngeal and laryngeal squamous cell carcinoma patients. There is no evidence for a better survival for p16 positive or HPV positive patients with hypopharyngeal or laryngeal squamous cell carcinoma. HPV seems to play a minor role in these entities of head and neck carcinoma.
Keyphrases
- squamous cell
- squamous cell carcinoma
- high grade
- end stage renal disease
- ejection fraction
- free survival
- chronic kidney disease
- lymph node metastasis
- papillary thyroid
- newly diagnosed
- prognostic factors
- cervical cancer screening
- electronic health record
- peritoneal dialysis
- smoking cessation
- young adults
- rectal cancer
- childhood cancer
- data analysis