Neuroprotection is improved by watertightness of fetal spina bifida repair in fetal lamb.
Luc JoyeuxJ van der MerweMichael AertsenP A PatelA KhatounM G M C Mori da CunhaS De VleeschauwerJ ParraE DanzerM McLaughlinD StoyanovTom VercauterenS OurselinE RadaelliP de CoppiF Van CalenberghJan A DeprestPublished in: Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology (2022)
A watertight layered fetal SBA repair improves brain and spinal cord structure and function in the fetal lamb model. This translational research has important clinical implication and neurosurgical technique that achieves watertightness should be adopted in all fetal centers to improve neuroprotection. Future clinical studies could assess whether the high quality of the repair correlates with clinical outcomes for neuroprotection. This article is protected by copyright. All rights reserved.