Role of epigenetics in unicellular to multicellular transition in Dictyostelium.

Simon Yuan WangElizabeth Ann PollinaI-Hao WangLindsay Kristina PinoHenry L BushnellKen TakashimaColette FritscheGeorge SabinBenjamin Aaron GarciaPaul Lieberman GreerEric Lieberman Greer

Published in: Genome biology (2021)

These results highlight the importance of epigenetics in reorganizing chromatin architecture to facilitate multicellularity in Dictyostelium discoideum and raise exciting possibilities about the role of epigenetics in the evolution of multicellularity more broadly.

Keyphrases

gene expression
dna damage
transcription factor
genome wide
oxidative stress
dna methylation