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Advanced diffusion imaging reveals microstructural characteristics of primary CNS lymphoma, allowing differentiation from glioblastoma.

Urs WürtembergerMartin DieboldAlexander RauVeysel AkgünLucas BeckerJürgen BeckPeter C ReinacherChristian A TaschnerMarco ReisertLuca FehrenbacherDaniel ErnyFlorian SchererMarc HohenhausHorst UrbachTheo Demerath
Published in: Neuro-oncology advances (2024)
Advanced diffusion imaging enables the characterization of the microstructure of PCNSL and reliably distinguishes PCNSL from GBM. Both imaging and histopathology revealed a relatively increased cell density and a preserved axonal microstructure in PCNSL.
Keyphrases
  • high resolution
  • white matter
  • single cell
  • stem cells
  • blood brain barrier
  • mass spectrometry
  • fluorescence imaging
  • bone marrow