Dual-phase [18F]florbetapir in frontotemporal dementia.
Michael AsgharRainer HinzKarl HerholzStephen F CarterPublished in: European journal of nuclear medicine and molecular imaging (2018)
This investigation demonstrates that early phase florbetapir uptake shows a reduction of frontal lobe perfusion in bvFTD, similar to metabolic findings with FDG. Thus, dynamic florbetapir scans can serve as a dual-phase biomarker in dementia patients to distinguish FTD from AD and cognitively normal elderly, removing the need for a separate FDG-PET scan in challenging dementia cases.
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