MODERATE ALCOHOL CONSUMPTION INDUCES LASTING IMPACTS ON PREFRONTAL CORTICAL SIGNALING IN MICE.
Grace C SmithKeith R GriffithAvery R SicherDakota F BrockwayElizabeth A ProctorNicole A CrowleyPublished in: bioRxiv : the preprint server for biology (2024)
Moderate voluntary alcohol consumption leads to disruption of prefrontal cortical signaling at protracted ages in both male and female miceExcitatory glutamatergic events onto prelimbic cortex GABAergic neurons, but not pyramidal neurons, are increased 6 months following alcohol exposureBoth pyramidal neurons and GABAergic neurons show altered intrinsic excitability 6 months following alcohol exposure.