NFE2L2 Mutations Enhance Radioresistance in Head and Neck Cancer by Modulating Intratumoral Myeloid Cells.
Li GuanDhanya K NambiarHongbin CaoVignesh ViswanathanShirley KwokAngela B Y HuiYuan HouRachel D HildebrandRie von EybenBrittany J HolmesJunfei ZhaoChristina S KongNathan WamsleyWeiruo ZhangMichael B MajorSeung W SeolJohn B SunwooDavid Neil HayesMaximillian DiehnQuynh-Thu LePublished in: Cancer research (2023)
NFE2L2 mutations are predictive biomarkers of radioresistance in head and neck cancer and confer sensitivity to glutaminase inhibitors to overcome radioresistance.