Combined plasma levels of IL-10 and testosterone, but not soluble HLA-G5, predict the risk of death in COVID-19 patients.
Giada AmodioPaolo CapogrossoMarina PontilloMichela TassaraLuca BoeriCristina CarenziDaniele CignoliAnna Maria FerraraGiuseppe A RamirezCristina TresoldiMassimo LocatelliLuca SantoleriAntonella CastagnaAlberto ZangrilloFrancesco De CobelliMoreno TresoldiGiovanni LandoniPatrizia Rovere-QueriniFabio CiceriFrancesco MontorsiAlessia d'ArmaSilvia GregoriPublished in: Andrology (2022)
Our findings indicate that combined evaluation of IL-10 and testosterone predicts the risk of death in men with COVID-19 and support the hypothesis that IL-10 fails to suppress excessive inflammation by promoting viral spreading.