Evidence of latent HPV infection in older Danish women with a previous history of cervical dysplasia.
Anne HammerJan BlaakærMaurits N C de KoningTorben SteinicheElse MejlgaardHans SvanholmMette T RoensboKatrine FuglsangJohn DoorbarRikke H AndersenWim G V QuintPatti E GravittPublished in: Acta obstetricia et gynecologica Scandinavica (2022)
HPV can be detected in cervical tissue specimens without any evidence of an active HPV infection, indicative of a latent, immunologically controlled infection. Modeling studies should consider including a latent state in their model when estimating the appropriate age to stop screening and when evaluating the impact of HPV vaccination.