The preimplantation genetic testing for monogenic disorders strategy for blocking the transmission of hereditary cancers through haplotype linkage analysis by karyomapping.
Chuanju ChenHao ShiWenbin NiuXiao BaoJingya YangHaixia JinWenyan SongYing-Pu SunPublished in: Journal of assisted reproduction and genetics (2023)
Our strategy has been proven to be feasible. It can effectively prevent transmission of hereditary cancer-related mutations to offspring during the prenatal stage.