The association between apolipoprotein A-1 plasma level and premature coronary artery disease: A systematic review and meta-analysis.
Mohammad Haji AghajaniArian Madani NeishabooriKoohyar AhmadzadehAmirmohammad TolouiMahmoud YousefifardPublished in: International journal of clinical practice (2021)
In conclusion, there seems to be a significant association between the serum levels of ApoA-1 and pCAD. However, all of the included studies had a case-control design and since there is no good quality and prospective cohort studies included, reliability of the current evidence is debatable. Therefore, further well-designed cohort studies are required to assess the impact of serum ApoA-1 reduction on pCAD onset.