Cost-consequence analysis of extended loading dose of anti-VEGF treatment in diabetic macular edema patients.
J M Ruiz-MorenoFernando de Andrés-NogalesItziar OyagüezPublished in: BMC ophthalmology (2020)
To extend the anti-VEGF loading dose from 3 to 6 injections necessitates investing €5882.77 (8 injections), €10,091.03 (14 injections) and €10,198.59 (30 injections) per additional responder patient (3-month nonresponders and 6-month responders) to aflibercept, ranibizumab and bevacizumab, respectively. For the total of patients treated, on average €7927.02 (14 injections) per additional responder patient would be needed.