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Implication of the Gut Microbiota in Metabolic Inflammation Associated with Nutritional Disorders and Obesity.

Nathalie M DelzenneMarta OlivaresNathalie M Delzenne
Published in: Molecular nutrition & food research (2020)
This review describes the role of nutrition as a modulator of metabolic regulation and focuses on the contribution of the gut microbiota in the process of the production of a large diversity of bioactive metabolites. The two first sections of the review will be dedicated to the impact of nutritional disorders on both the gut microbiota composition and on metabolic inflammation. The last and more prominent section will describe the role of different nutrient-derived gut metabolites on the gut barrier integrity, metabolic inflammation, and peripheral tissue alterations during obesity or associated complications.
Keyphrases
  • oxidative stress
  • metabolic syndrome
  • insulin resistance
  • weight loss
  • type diabetes
  • ms ms
  • weight gain
  • physical activity
  • high fat diet induced
  • skeletal muscle
  • adipose tissue
  • body mass index