Vexin is upregulated in cerebral cortical neurons by brain-derived neurotrophic factor.
Hisatsugu KoshimizuShingo SuzukiAnna KawaiRyuichiro MiuraKen-Ichi OhtaTakanori MikiNaoki AdachiHidetada MatsuokaPublished in: Neuropsychopharmacology reports (2020)
The upregulated H3K27ac in the brain may be associated with the enriched gene expression of Vexin in the brain. It is indicated that BDNF induces the gene expression of Vexin in the cortical neurons via the TrkB-MEK signaling pathway.
Keyphrases
- gene expression
- signaling pathway
- resting state
- dna methylation
- white matter
- cerebral ischemia
- spinal cord
- pi k akt
- functional connectivity
- subarachnoid hemorrhage
- multiple sclerosis
- epithelial mesenchymal transition
- brain injury
- spinal cord injury
- blood brain barrier
- cell proliferation
- oxidative stress
- stress induced
- induced apoptosis