Integrated HBV DNA and cccDNA maintain transcriptional activity in intrahepatic HBsAg-positive patients with functional cure following PEG-IFN-based therapy.

Na Gao Guiwen GuanGanlin XuHaishi Wu Chan XieZhishuo MoHong DengShuying XiaoZhicong DengLiang PengFeng-Min Lu Qi-Yi Zhao Zhi-Liang Gao

Published in: Alimentary pharmacology & therapeutics (2023)

Integrated HBV DNA and cccDNA maintain transcriptional activity and maybe involved in HBsAg seroreversion in intrahepatic HBsAg-positive patients with functional cure and linked to virological relapse.

Keyphrases

hepatitis b virus
circulating tumor
liver failure
cell free
single molecule
transcription factor
immune response
drug delivery
dendritic cells
hiv infected
heat shock
nucleic acid
oxidative stress
mesenchymal stem cells