FoxP3+ regulatory T cells, interleukin 17 and mast cells in chronic inflammatory periodontal disease.

V P B Parachuru Dawn Elizabeth CoatesT J MilneA M RichG J Seymour

Published in: Journal of periodontal research (2018)

Based on the findings of this study, we suggest that the source of low levels of IL17A in periodontal tissues is mast cells not Th17 cells and that Tregs may have a more prominent role in the pathogenesis of periodontal disease than Th17 cells.

Keyphrases

regulatory t cells
induced apoptosis
cell cycle arrest
dendritic cells
oxidative stress
cell proliferation
immune response