Swim-up method is superior to density gradient centrifugation for preserving sperm DNA integrity during sperm processing.

Kenji AmanoSatoko OigawaKoichiro IchizawaYukiko TokudaMami UnagamiMami SekiguchiMayuko FuruiKentaro NakaokaAyumu ItoRika HayashiYuko TamakiYuko HayashiYusuke FukudaYukiko KatagiriMasahiko NakataKoichi Nagao

Published in: Reproductive medicine and biology (2024)

The swim-up method is superior to density gradient centrifugation, evidenced by less sperm DNA fragmentation and higher sperm progressive motility. The recovery rate of progressive motile sperms was better after density gradient centrifugation than after swim-up.

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