Oxidative phenotype induced by aerobic physical training prevents the obesity-linked insulin resistance without changes in gastrocnemius muscle ACE2-Angiotensin(1-7)-Mas axis.

Bruno VecchiattoRafael C da SilvaTalita S HigaCynthia R MullerAnna Laura V AméricoVanessa C Fortunato-LimaMarília M FerreiraLuiz Felipe MartucciMiriam H Fonseca-AlanizFabiana Sant'Anna Evangelista

Published in: Diabetology & metabolic syndrome (2021)

The APT prevents obesity-linked IR by modifying the skeletal muscle phenotype to one more oxidative independent of changes in the muscle ACE2/Ang 1-7/Mas axis.

Keyphrases

insulin resistance
skeletal muscle
angiotensin ii
angiotensin converting enzyme
high fat diet induced
high fat diet
polycystic ovary syndrome
metabolic syndrome
adipose tissue
type diabetes
physical activity
mental health
mouse model
weight loss
high intensity
virtual reality