SLIT3 promotes myogenic differentiation as a novel therapeutic factor against muscle loss.

Han Jin ChoHyeonmok KimYoung-Sun LeeSung Ah MoonJin-Man KimHanjun KimMin Ji KimJiyoung YuKyunggon KimIn-Jeoung BaekSeung Hun LeeKyong Hoon AhnSungsub KimJong-Sun KangJung-Min Koh

Published in: Journal of cachexia, sarcopenia and muscle (2021)

SLIT3 plays a sarcoprotective role by activating β-catenin signalling. SLIT3 LRRD2 can potentially be used as a therapeutic agent against muscle loss.

Keyphrases

skeletal muscle
signaling pathway
cell proliferation