Association of combined complement factor H Y402H and ARMS2/LOC387715 A69S polymorphisms with age-related macular degeneration: an updated meta-analysis.

Mohammad Hossein Jabbarpoor BonyadiMehdi YaseriMasoud Soheilian

Published in: Ophthalmic genetics (2020)

This updated analysis showed a strong synergistic and positive multiplicative effect of these two genes indicating that there is common pathway of ARMS2/LOC387715 A69 S and CFH Y402 H in AMD pathogenesis which may be complement system pathway.

Keyphrases

age related macular degeneration
systematic review
genome wide
cancer therapy
dna methylation