Repeated rectal application of a hyperosmolar lubricant is associated with microbiota shifts but does not affect PrEP drug concentrations: results from a randomized trial in men who have sex with men.

Richard E Haaland Jeffrey FountainYingtian HuAngela HolderChuong DinhLaShonda HallNicole A PescatoreSheila HeekeClyde E HartJiahui XuYi-Juan HuColleen F Kelley

Published in: Journal of the International AIDS Society (2019)

Repeated rectal application of a hyperosmolar lubricant does not affect mucosal PrEP drug concentrations but is associated with changes in the rectal microbiome.

Keyphrases

men who have sex with men
hiv testing
hiv positive
rectal cancer
adverse drug
hiv infected
human immunodeficiency virus