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Proteus: An algorithm for proposing stabilizing mutation pairs based on interactions observed in known protein 3D structures.

José Renato M S BarrosoDiego César Batista MarianoSandro R DiasRafael E O RochaLucianna H SantosRonaldo A P NagemRaquel C de Melo-Minardi
Published in: BMC bioinformatics (2020)
We believe that Proteus could be used combined with other methods to give new insights into the rational development of engineered proteins. Proteus user-friendly web-based tool is available at < http://proteus.dcc.ufmg.br >.
Keyphrases
  • machine learning
  • deep learning
  • high resolution
  • mass spectrometry
  • amino acid
  • binding protein
  • low cost