Experimental rhinovirus infection induces an antiviral response in circulating B cells which is dysregulated in patients with asthma.
Oliver Fabian WirzKirstin JansenPattraporn SatitsuksanoaWillem van de VeenGe TanMilena SokolowskaDavid MirerBarbara StanićSimon D MessageTatiana KebadzeNicholas GlanvillePatrick MalliaJames E GernNikolaos PapadopoulosMübeccel AkdisSebastian L JohnstonKari Christine NadeauMübeccel AkdişPublished in: Allergy (2021)
These findings add to the understanding of systemic effects of rhinovirus infections on B-cell responses in the periphery, show potential dysregulation in patients with asthma and might also have implications during infection with other respiratory viruses.