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Addition of Everolimus Post VEGFR Inhibition Treatment Failure in Advanced Sarcoma Patients Who Previously Benefited from VEGFR Inhibition: A Case Series.

Adam C ElNaggarJohn L HaysJames L Chen
Published in: PloS one (2016)
In this heavily pre-treated, advanced sarcoma population, the addition of mTOR inhibition to VEGFRi based therapy resulted in a clinical benefit for a subset of patients. Prospective studies will be needed to verify these results.
Keyphrases
  • newly diagnosed
  • end stage renal disease
  • ejection fraction
  • vascular endothelial growth factor
  • peritoneal dialysis
  • stem cells
  • bone marrow
  • endothelial cells
  • chemotherapy induced